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PUBLICATIONS: Sibylle Brenner


Brenner, S., F. Berger, L. Rao, M. P. Nicholas, and A. Gennerich. Force production of human cytoplasmic dynein is limited by its processivity. 2020. Sci. Adv. 6:eaaz4295. [pdf]


Nicholas, M. P., F. Berger, L. Rao, S. Brenner, C. Cho, and A. Gennerich. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. 2015. Proc. Natl. Acad. Sci. USA, 12:6371-6376. [pdf]

Nicholas, M. P.*, P. Hook*, S. Brenner, C. Lazar, R. B. Vallee#, and A. Gennerich#. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. 2015. Nat. Commun., 6:6206 (*: Co-first authors; #: co-corresponding authors). [pdf]


Rao, L.*, E. M. Romes*, M. P. Nicholas, S. Brenner, T. Ashutosh, A. Gennerich#, and K. C. Slep#. The yeast dynein dyn2-pac11 complex is a dynein dimerization/processivity factor: structural and single molecule characterization. 2013. Mol. Biol. Cell (*: co-first authors; #: co-corresponding authors). [pdf]


Leferink, N. G., C. R. Pudney, S. Brenner, D. J. Heyes, R. R. Eady, S. S. Hasnain, S. Hay, S. E. Rigby, and N. S. Scrutton. Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase. 2011. FEBS Lett. 586:578-584. [pdf]


Hay, S., S. Brenner, B. Khara, A. M. Quinn, S. E. Rigby, and N. S. Scrutton. Nature of the energy landscape for gated electron transfer in a dynamic redox protein. 2010. J. Am. Chem. Soc. 132:9738-9745. [pdf]


Brenner, S., D. J. Heyes, S. Hay, M. A. Hough, R. R. Eady, S. S. Hasnain, and N. S. Scrutton. Demonstration of proton-coupled electron transfer in copper-containing nitrite reductases. 2009. J. Biol. Chem. 284:25973-25983. [pdf]

Brenner, S., S. Hay, and N. S. Scrutton. Ionic Strength Dependence of the Heating Time in T-Jump Instrument TJ-64. 2009. Hi-Tech Scientific AN.020.T64.


Wohlgemuth, I., S. Brenner, M. Beringer, and M. V. Rodnina. Modulation of the rate of peptidyl transfer on the ribosome by the nature of substrates. 2008. J. Biol. Chem. 283:32229-32235. [pdf]

Brenner, S., S. Hay, A. W. Munrow, and N. S. Scrutton. Inter-flavin electron transfer in cytochrome P450 reductase - effects of solvent and pH identify hidden complexity in mechanism. 2008. FEBS J. 275:4540-4557. [pdf]


Brenner, S., S. Hay, H. M. Girvan, A. W. Munro, and N. S. Scrutton. Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy. 2007. J. Phys. Chem. B 111:7879-7886. [pdf]


Brenner, S., S. Hay, and N. S. Scrutton. Temperature calibration of T-Jump Instrument TJ-64 using Tris/Phenol Red. 2006. Hi-Tech Scientific AN.019.T64.