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PUBLICATIONS: Matthew Nicholas


Brenner, S., F. Berger, L. Rao, M. P. Nicholas, and A. Gennerich. Force production of human cytoplasmic dynein is limited by its processivity. 2020. Science Advances (in press).


Rao, L., F. Berger, M. P. Nicholas, and A. Gennerich. Molecular mechanism of cytoplasmic dynein tension sensing. 2019. Nat. Commun. 10:3332. [pdf]


Nicholas, M. P., F. Berger, L. Rao, S. Brenner, C. Cho, and A. Gennerich. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. 2015. Proc. Natl. Acad. Sci. USA, 12:6371-6376. [pdf]

Nicholas, M. P.*, P. Hook*, S. Brenner, C. Lazar, R. B. Vallee#, and A. Gennerich#. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. 2015. Nat. Commun., 6:6206 (*: Co-first authors; #: co-corresponding authors). [pdf]


Nicholas, M. P., L. Rao, and A. Gennerich. Covalent immobilization of microtubules on glass surfaces for molecular motor force measurements and other single-molecule assays. 2014. Methods Mol. Biol., 1136:137-169. [pdf]

Nicholas, M. P., L. Rao, and A. Gennerich. An improved optical tweezers assay for measuring the force generation of single kinesin molecules. 2014. Methods Mol. Biol., 1136:171-246. [pdf]


Rao, L.*, E. M. Romes*, M. P. Nicholas, S. Brenner, T. Ashutosh, A. Gennerich#, and K. C. Slep#. The yeast dynein dyn2-pac11 complex is a dynein dimerization/processivity factor: structural and single molecule characterization. 2013. Mol. Biol. Cell, 24:2362-2377 (*: co-first authors; #: co-corresponding authors). [pdf]


Nicholas, M. P., E. Ertan, F. Fabien, C. David, and G. Ranajeet. Nuclear spin relaxation in isotropic and anisotropic media. 2010. Progress in nuclear magnetic resonance spectroscopy 57:111-158. [pdf]